Publicaciones científicas

What Have We Learned about the Prevention of NMSC from Albino Patients from Malawi? Secondary Prevention Maintained over Time

16-abr-2024 | Revista: Cancers

Alejandra Tomás-Velázquez  1 , Ester Moreno-Artero  2 , Javier Romero  3 , Pilar Escalonilla  4 , Isabel Medina  3 , Gisela Hebe Petiti  5 , Pedro Redondo  1

Background: We have conducted cooperative campaigns focusing on albino patients in a rural area of Malawi. What have we learned?

Methods: Three surgical campaigns were performed in Nkhotakota district (2019-2023). Albino clinical and tumor characteristics were collected.

Results: Between 22 and 75 albinos were evaluated in each campaign (mean age < 28 years old). Most patients did not use sunscreen in a way that provided optimal photoprotection. Regarding tumors, the proportion of basal and squamous cell carcinomas ranged from 1:1 to almost 2:1. Of 156 albino patients, 34 attended more than once. However, of the 19 patients with 30 tumors operated on in 2021, only seven were assessed the following year (12 were lost to follow-up). At least 14 albinos with locally advanced tumors were evaluated.

Conclusions: Distributing photoprotective clothing could be more efficient or perhaps an earlier measure of sunscreen in rural Africa as it does not require permanent repositioning. Very-high-risk patients (previous interventions with positive margins or high-risk tumors, intense actinic damage, and new tumors constantly appearing, especially those presenting SCCs) require close follow-up and treatment and represent our main target. Secondary prevention with Malawian collaboration and the use of teledermatology is essential for patient tracking, as they are able to offer curative treatments.

CITA DEL ARTÍCULO  Cancers (Basel). 2024 Apr 16;16(8):1522. doi: 10.3390/cancers16081522