Publicaciones científicas

Pathogenesis of Alzheimer's disease

01-ene-1997 | Revista: Revista de Medicina de la Universidad de Navarra

Alegre M., Noé E., Luquin M.R.
Departamento de Neurología, Clínica Universitaria, Facultad de Medicina, Universidad de Navarra


Alzheimer's disease (AD) is a multifactorial entity with a complex pathogeny. Recent findings on this subject are discussed in this article, centering mainly on genetic factors, cerebral ischemia and their association with the most typical histologic lesions in AD.

Finally, a hypothetical model is proposed, in which beta-amyloid represents the key element.

CITA DEL ARTÍCULO  Rev Med Univ Navarra. 1997 Jan-Mar;41(1):46-57