Publicaciones científicas

Obesity and COVID-19: A Perspective from the European Association for the Study of Obesity on Immunological Perturbations, Therapeutic Challenges, and Opportunities in Obesity

13-ago-2020 | Revista: Obesity Facts

Gijs H Goossens  1   2 , Dror Dicker  3   4 , Nathalie J Farpour-Lambert  3   5 , Gema Frühbeck  3   6 , Dana Mullerova  3   7 , Euan Woodward  3   8 , Jens-Christian Holm  3   9


Abstract

Accumulating evidence suggests that obesity is a major risk factor for the initiation, progression, and outcomes of coronavirus disease 2019 (COVID-19).

The European Association for the Study of Obesity (EASO), as a scientific and medical society dedicated to the promotion of health and well-being, is greatly concerned about the concomitant obesity and COVID-19 pandemics and their impact on health and society at large.

In this perspective, we will address the inherent immunological perturbations and alterations in the renin-angiotensin-aldosterone system in patients with obesity and COVID-19, and discuss how these impairments may underlie the increased susceptibility and more detrimental outcomes of COVID-19 in people with obesity.

Clearly, this has important implications for preventive measures, vaccination, and future therapeutic strategies to combat COVID-19.

Furthermore, we will highlight important knowledge gaps and provide suggestions for future research and recommendations for policy actions. Since many new reports on COVID-19 rapidly appear, the present perspective should be seen as a focus for discussion to drive forward further understanding, research initiatives, and clinical management of COVID-19.

CITA DEL ARTÍCULO  Obes Facts. 2020 Aug 13;1-14. doi: 10.1159/000510719

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