Publicaciones científicas

Nuclear factor k B is activated in myelodysplastic bone marrow cells

01-sep-2002 | Revista: Haematologica

Sanz C, Richard C, Prosper F, Fernandez-Luna JL.

We describe a significant increase in the DNA binding activity of nuclear factor-kappa B (NF kappa B) in bone marrow cells from patients with myelodysplastic syndrome (MDS) compared with normal donor cells.

Furthermore, MDS samples with increased NFkappaB activity consistently showed higher mRNA levels of NFkappaB-regulated cytokines.

CITA DEL ARTÍCULO  Haematologica. 2002 Sep;87(9):1005-6