Publicaciones científicas

Minimally invasive liver surgery for hepatocellular carcinoma in patients with portal hypertension

07-mar-2023 | Revista: BJS Open

Daniel Aliseda  1 , Gabriel Zozaya  1   2 , Pablo Martí-Cruchaga  1   2 , Juan Lujan  1 , Ana Almeida  1 , Nuria Blanco  1 , Lucas Sabatella  1 , Bruno Sangro  2   3 , Fernando Rotellar  1   2


For patients with early stage hepatocellular carcinoma (HCC), liver resection is a mainstay of curative treatment. Patients with a solitary tumour, Child–Pugh A cirrhosis and serum bilirubin of 1 mg/dl are considered ideal candidates for liver resection1,2.

For patients with portal hypertension, current guidelines recommend careful consideration of liver resection based on the hierarchical interaction of portal hypertension, liver function and resection extent1,3.

Open liver resection has been used in the majority of published studies on liver resection and portal hypertension. Although there is limited published experience of minimally invasive liver resection (MILR), using MILR in these patients appears to be associated with favourable outcomes4.

Particularly in patients with Child–Pugh A cirrhosis, but also in patients with more advanced cirrhosis5, MILR offers significant advantages in the surgical treatment of HCC including reduced intraoperative bleeding, fewer complications and minimized surgical aggression, which improves recovery6,7.

If these benefits are also found in patients with portal hypertension, MILR may represent a step forward in the surgical treatment of patients with HCC and portal hypertension.

CITA DEL ARTÍCULO  BJS Open. 2023 Mar 7;7(2):zrad037. doi: 10.1093/bjsopen/zrad037