Publicaciones científicas

Generation of four Isl1 reporter iPSC lines from cardiac and tail-tip fibroblasts derived from Ai6IslCre mouse

01-dic-2018 | Revista: Stem Cell Research

Linares J (1), López-Muneta L (1), Arellano-Viera E (1), Ripalda-Cemboráin P (2), Iglesias E (1), Abizanda G (3), Aranguren XL (1), Prósper F (3), Carvajal-Vergara X (4).

(1) Cell Therapy Program, Center for Applied Medical Research (CIMA), University of Navarra, Instituto de Investigación Sanitaria de Navarra, Pamplona, Spain.
(2) Laboratory of Experimental Orthopaedics, Clínica Universidad de Navarra, Pamplona, Spain.
(3) Cell Therapy Program, Center for Applied Medical Research (CIMA), University of Navarra, Instituto de Investigación Sanitaria de Navarra, Pamplona, Spain; Cell Therapy Area, Clínica Universidad de Navarra, University of Navarra, Instituto de Investigación Sanitaria de Navarra, Pamplona, Spain.
(4) Cell Therapy Program, Center for Applied Medical Research (CIMA), University of Navarra, Instituto de Investigación Sanitaria de Navarra, Pamplona, Spain.


RESUMEN

Islet-1 (Isl1) is a transcription factor essential for life expressed in specific cells with different developmental origins. We have generated iPSC lines from fibroblasts of the transgenic Ai6 x Isl1-Cre (Ai6IslCre) mouse.

Here we describe the complete characterization of four iPSC lines: ATCi-Ai6IslCre10, ATCi-Ai6IslCre35, ATCi-Ai6IslCre74 and ATCi-Ai6IslCre80.

CITA DEL ARTÍCULO  Stem Cell Res. 2018 Dec;33:125-129. doi: 10.1016/j.scr.2018.10.013. Epub 2018 Oct 11

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