Publicaciones científicas

Dopamine agonists suppress visual-cortical reflex myoclonus

01-dic-1985 | Revista: Journal of Neurology, Neurosurgery and Psychiatry

Obeso JA, Artieda J, Tuñón T, Luquin MR, Martínez Lage JM.

Two patients with a diagnosis of olivo-ponto-cerebellar atrophy developed cortical reflex myoclonus to visual (flash) and somaesthetic stimuli.

Oral treatment with levodopacarbidopa (1000/100 mg) or subcutaneous administration of apomorphine (1 mg) abolished the visually-triggered myoclonus, without modifying reflex myoclonus to electrical or tactile stimulation. Intravenous administration of lisuride (0.1 mg) produced a marked reduction in both types of reflex myoclonus.

These results indicate a selective inhibitory effect of dopamine agonist drugs on visual reflex myoclonus of cortical origin.

CITA DEL ARTÍCULO  J Neurol Neurosurg Psychiatry. 1985 Dec;48(12):1277-83