Publicaciones científicas

Clonal transmission of NDM-5-producing Escherichia coli belonging to high-risk sequence type ST405

01-jul-2018 | Revista: International Journal of Antimicrobial Agents

Barrado L (1), Pérez-Vázquez M (2), Luis Del Pozo J (3), Martín-Salas C (4), Leiva J (5), Mazón A (4), Ezpeleta C (4), Oteo J (6).


Carbapenemase-producing Enterobacteriaceae are a critical public-health problem. The European Survey on Carbapenemase-Producing Enterobacteriaceae (EuSCAPE) reported that 19% of carbapenem-non-susceptible Escherichia coli isolates produced carbapenemases [1].

In Spain, an upward trend in carbapenemase-producing E. coli has been observed, mainly due to the dissemination of OXA-48 [2]; however, sporadic occurrence of NDM-producers has been reported [2] ;  [3].

The success of high-risk E. coli clones might be due to factors such as increased transmission and colonisation capacity, antibiotic multiresistance and enhanced virulence.

CITA DEL ARTÍCULO  Int J Antimicrob Agents. 2018 Jul;52(1):123-124.
doi: 10.1016/j.ijantimicag.2018.05.018. Epub 2018 Jun 1.