Publicaciones científicas

Acute kidney injury after cardiac surgery: prevalence, impact and management challenges

02-jul-2019 | Revista: International Journal of Nephrology Renovascular Disease

M Vives  1 , A Hernandez  2 , F Parramon  3 , N Estanyol  3 , B Pardina  3 , A Muñoz  3 , P Alvarez  4 , C Hernandez  3


Acute kidney injury (AKI) is a major medical problem that is of particular concern after cardiac surgery. Perioperative AKI is independently associated with an increase in short-term morbidity, costs of treatment, and long-term mortality.

In this review, we explore the definition of cardiac surgery-associated acute kidney injury (CSA-AKI) and identify diverse mechanisms and risk factors contributing to the renal insult.

Current theories of the pathophysiology of CSA-AKI and description of its clinical course will be addressed in this review. Data on the most promising renal protective strategies in cardiac surgery, from well-designed studies, will be scrutinized. Furthermore, diagnostic tools such as novel biomarkers of AKI and their potential utility will be discussed.

CITA DEL ARTÍCULO  Int J Nephrol Renovasc Dis. 2019 Jul 2;12:153-166.  doi: 10.2147/IJNRD.S167477. eCollection 2019.