Publicaciones científicas

Transcranial static magnetic field stimulation (tSMS) of the visual cortex decreases experimental photophobia

01-ene-2017 | Revista: Cephalalgia

Lozano-Soto E (1), Soto-León V (1), Sabbarese S (1), Ruiz-Alvarez L (1,2), Sanchez-Del-Rio M (3), Aguilar J (4), Strange BA (5,6), Foffani G (7,8), Oliviero A (1).

(1) FENNSI Group, Hospital Nacional de Parapléjicos, SESCAM, Toledo, Spain.
(2) Neurology Service, Hospital del Henares. Coslada, Madrid, Spain.
(3) Neurology Department, Hospital Ruber Internacional, Madrid, Spain.
(4) Experimental Neurophysiology Group, Hospital Nacional de Parapléjicos, SESCAM, Toledo, Spain.
(5) Laboratory for Clinical Neuroscience, CTB, 16771 Universidad Politecnica de Madrid , Madrid, Spain.
(6) Department of Neuroimaging, Alzheimer's Disease Research Centre, Reina Sofia-CIEN Foundation, Madrid, Spain.
(7) HM CINAC, Hospital Universitario HM Puerta del Sur, Universidad CEU-San Pablo, Madrid, Spain.
(8) Neural Bioengineering Group, Hospital Nacional de Parapléjicos, SESCAM, Toledo, Spain.


Background
Transcranial static magnetic field stimulation (tSMS) reduces cortical excitability in humans.

Methods
The objective of this study was to determine whether tSMS over the occipital cortex is effective in reducing experimental photophobia. In a sham-controlled double-blind crossover study, tSMS (or sham) was applied for 10 minutes with a cylindrical magnet on the occiput of 20 healthy subjects.

We assessed subjective discomfort induced by low-intensity and high-intensity visual stimuli presented in a dark room before, during and after tSMS (or sham).

Results
Compared to sham, tSMS significantly reduced the discomfort induced by high-intensity light stimuli.

Conclusions
The visual cortex may contribute to visual discomfort in experimental photophobia, providing a rationale for investigating tSMS as a possible treatment for photophobia in migraine.

CITA DEL ARTÍCULO  Cephalalgia. 2017 Jan 1:333102417736899. doi: 10.1177/0333102417736899

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