Publicaciones científicas

The significance of the omentum in locoregional immunotherapy for peritoneal carcinomatosis

20-nov-2023 | Revista: Oncoimmunology

Ángela Bella  1   2 , Ignacio Melero  1   2   3   4   5 , Pedro Berraondo  1   2   3 , Fernando Aranda  1   2


Abstract

Our recent research has unveiled the potential of locoregional immunotherapy. Cytokine-armored viral vectors, such as modified vaccinia virus Ankara vector encoding single-chain interleukin-12 (MVA.scIL-12), can target the omentum and elicit a robust tumor-specific immune response, all the while minimizing toxicity.

CITA DEL ARTÍCULO  Oncoimmunology. 2023 Nov 20;12(1):2285106.  doi: 10.1080/2162402X.2023.2285106. eCollection 2023.