The role of leukotrienes and other eicosanoids in the response to an allograft. New perspectives on the control of rejection.
González Fernández J, Alvarez-Cienfuegos J, Pardo Sánchez F, Benito Fernández C, Balen Rivera E.
Departamento de Cirugía General, Clínica Universitaria de Navarra, Pamplona.
The role of eicosanoids in the development of immune response may be important to the viability of the implanted organ, given their complicated interaction with lymphokines and monokines which regulate the response.
Due to this reason, more experiments in vivo are necessary to provide a better understanding of the behaviour of these compounds.
This would help to clearly determine the role of these substances in the immune response--more exactly, in the allogenic transplant rejection--creating new ways for its control.
CITA DEL ARTÍCULO An Med Interna. 1991 Apr;8(4):194-8