Publicaciones científicas

Advances in Graves' disease

Galofré JC, Duntas LH, Premawardhana LD, Davies TF.
Department of Endocrinology and Nutrition, Clinica Universidad de Navarra, 36 Pio XII Avenue, 31080 Pamplona, Spain

Revista: Journal of Thyroid Research

Fecha: 20-may-2012

Endocrinología y Nutrición


It was Dr. Robert J. Graves who used to pronounce this statement at the inauguration of his yearly university lectures in Dublin. This was in the nineteen century and he had only just described Graves’ disease, the most common hyperthyroid condition that is so widely recognized today.

There could be at least two complementary ways of interpreting Dr. Graves’ perennial advice. The first way is from a practical viewpoint. It emphasizes the importance of observation and monitoring clinical evolution. This is an important good-practice guide for doctors (and students) that are at a patient’s bedside. This practical approach promotes a deep scrutiny of the disease, taking into consideration that it is not an abstract concept, but an ailment embodied in a given patient.

The second interpretation of Graves’ statement could be more theoretical. Thus the significance of the statement supports the concept of clinical and laboratory research. Physicians must participate in research at all levels: basic, translational, and clinical. Dr. Graves’ counsel encourages efforts to achieve a deep knowledge of disease as individual entities. Therefore, both objectives, practical and theoretical, are closely entwined—laboratory advances connected to the bedside—what we now call translational medicine. Unfortunately, this link is often weak.

CITA DEL ARTÍCULO  J Thyroid Res. 2012;2012:809231. Epub 2012 May 20



La Clínica es el hospital privado con mayor dotación tecnológica de España, todo en un único centro.

Imagen de un PET, tecnología de vanguardia en la Clínica Universidad de Navarra


Los profesionales de la Clínica realizan una labor continuada de investigación y formación, siempre en beneficio del paciente.

Imagen profesionales de la Clínica Universidad de Navarra


Conozca por qué somos diferentes a otros centros sanitarios. Calidad, rapidez, comodidad y resultados.

Imagen del edificio de la Clínica Universidad de Navarra