Publicaciones científicas

Advanced MR Techniques for Preoperative Glioma Characterization: Part 1

03-mar-2023 | Revista: Journal of Magnetic Resonance Imaging

Lydiane Hirschler  1 , Nico Sollmann  2   3   4 , Bárbara Schmitz-Abecassis  5   6 , Joana Pinto  7 , Fatemehsadat Arzanforoosh  8 , Frederik Barkhof  9   10 , Thomas Booth  11   12 , Marta Calvo-Imirizaldu  13 , Guilherme Cassia  14 , Marek Chmelik  15 , Patricia Clement  16   17 , Ece Ercan  5 , Maria A Fernández-Seara  13   18 , Julia Furtner  19   20 , Elies Fuster-Garcia  21 , Matthew Grech-Sollars  22   23 , Nazmiye Tugay Guven  24 , Gokce Hale Hatay  24 , Golestan Karami  11 , Vera C Keil  9   25 , Mina Kim  26 , Johan A F Koekkoek  27   28 , Simran Kukran  29   30 , Laura Mancini  23   31 , Ruben Emanuel Nechifor  32 , Alpay Özcan  33 , Esin Ozturk-Isik  24 , Senol Piskin  34 , Kathleen Schmainda  35 , Siri F Svensson  36   37 , Chih-Hsien Tseng  6   38 , Saritha Unnikrishnan  39   40 , Frans Vos  6   8   38 , Esther Warnert  8 , Moss Y Zhao  41   42 , Radim Jancalek  43   44 , Teresa Nunes  45 , Kyrre E Emblem  36 , Marion Smits  7   8   46 , Jan Petr  47 , Gilbert Hangel  48   49   50   51


Abstract

Preoperative clinical magnetic resonance imaging (MRI) protocols for gliomas, brain tumors with dismal outcomes due to their infiltrative properties, still rely on conventional structural MRI, which does not deliver information on tumor genotype and is limited in the delineation of diffuse gliomas.

The GliMR COST action wants to raise awareness about the state of the art of advanced MRI techniques in gliomas and their possible clinical translation or lack thereof.

This review describes current methods, limits, and applications of advanced MRI for the preoperative assessment of glioma, summarizing the level of clinical validation of different techniques.

In this first part, we discuss dynamic susceptibility contrast and dynamic contrast-enhanced MRI, arterial spin labeling, diffusion-weighted MRI, vessel imaging, and magnetic resonance fingerprinting.

The second part of this review addresses magnetic resonance spectroscopy, chemical exchange saturation transfer, susceptibility-weighted imaging, MRI-PET, MR elastography, and MR-based radiomics applications. Evidence Level: 3 Technical Efficacy: Stage 2.

CITA DEL ARTÍCULO J Magn Reson Imaging. 2023 Mar 3. doi: 10.1002/jmri.28662