Publicaciones científicas
Exploring the muscle architecture effect on the mechanical behaviour of mouse rotator cuff muscles
A Heras-Sádaba 1 , A Pérez-Ruiz 2 , P Martins 1 , C Ederra 2 , C Ortiz de Solórzano 2 , G Abizanda 2 , J Pons-Villanueva 3 , B Calvo 4 , J Grasa 5
Abstract
Incorporating detailed muscle architecture aspects into computational models can enable researchers to gain deeper insights into the complexity of muscle function, movement, and performance. In this study, we employed histological, multiphoton image processing, and finite element method techniques to characterise the mechanical dependency on the architectural behaviour of supraspinatus and infraspinatus mouse muscles.
While mechanical tests revealed a stiffer passive behaviour in the supraspinatus muscle, the collagen content was found to be two times higher in the infraspinatus. This effect was unveiled by analysing the alignment of fibres during muscle stretch with the 3D models and the parameters obtained in the fitting.
Therefore, a strong dependence of muscle behaviour, both active and passive, was found on fibre orientation rather than collagen content.
CITA DEL ARTÍCULO Comput Biol Med. 2024 Apr 2:174:108401. doi: 10.1016/j.compbiomed.2024.108401
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