Scientific publications

Utility of immunophenotypic and immunogenotypic analysis in the study of necrotic lymph nodes

Vega F, Lozano MD [SP], Alcalde J [SP], Pardo-Mindan FJ. [SP]
Department of Pathology, Clínica Universitaria de Navarra, Pamplona, Spain.

Magazine: Virchows Archive

Date: Mar 1, 1999

Otorhinolaryngology Pathological Anatomy [SP]

We report a case of complete lymph node necrosis.

No specific aetiology could be determined by morphology, but a B lymphoid population and clonal rearrangement of the immunoglobulin heavy chain gene were demonstrated in immunophenotypic and immunogenotypic studies performed using DNA extracted from paraffin embedded necrotic tissue. In the setting of lymph node necrosis, we suggest that immunohistochemical and gene rearrangement studies may provide additional diagnostic information.

CITATION  Virchows Arch. 1999 Mar;434(3):245-8

you maybe interested

WHAT TECHNOLOGY
DO WE USE?

The Clínica is the greater private hospital with technological equipment of Spain, all in a single center.

Imagen de un PET, tecnología de vanguardia en la Clínica Universidad de Navarra

OUR
PROFESSIONALS

The professionals of the Clínica perform continuous research and training, always to the benefit of the patient.

Imagen profesionales de la Clínica Universidad de Navarra

WHY CHOOSE
THE CLINICA?

Learn why we are different from other healthcare centers. Quality, speed, comfort and results.

Imagen del edificio de la Clínica Universidad de Navarra