Utility of immunophenotypic and immunogenotypic analysis in the study of necrotic lymph nodes
Magazine: Virchows Archive
Date: Mar 1, 1999Otorhinolaryngology Pathological Anatomy [SP]
We report a case of complete lymph node necrosis.
No specific aetiology could be determined by morphology, but a B lymphoid population and clonal rearrangement of the immunoglobulin heavy chain gene were demonstrated in immunophenotypic and immunogenotypic studies performed using DNA extracted from paraffin embedded necrotic tissue. In the setting of lymph node necrosis, we suggest that immunohistochemical and gene rearrangement studies may provide additional diagnostic information.
CITATION Virchows Arch. 1999 Mar;434(3):245-8
you maybe interested
The Clínica is the greater private hospital with technological equipment of Spain, all in a single center.
The professionals of the Clínica perform continuous research and training, always to the benefit of the patient.
Learn why we are different from other healthcare centers. Quality, speed, comfort and results.