The basal ganglia and disorders of movement: pathophysiological mechanisms
Obeso J.A., Rodríguez-Oroz M.C., Rodríguez M., Arbizu J [SP]., Giménez-Amaya J.M.
Department of Neurology, Clínica Universitaria and Medical School, University of Navarra, Pamplona 31008, Spain.
Magazine: News in Physiological Sciences
Date: Apr 1, 2002Nuclear Medicine [SP] Neurology [SP]
The basal ganglia are part of a neuronal network organized in parallel circuits.
The motor circuit is most relevant to the pathophysiology of movement. Abnormal increment or reduction in the inhibitory output activity of basal ganglia give rise, respectively, to poverty and slowness of movement (i.e., Parkinson's disease) or dyskinesias.
CITATION News Physiol Sci. 2002 Apr;17:51-5
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