Scientific publications

The basal ganglia and disorders of movement: pathophysiological mechanisms

Obeso J.A., Rodríguez-Oroz M.C., Rodríguez M., Arbizu J [SP]., Giménez-Amaya J.M.
Department of Neurology, Clínica Universitaria and Medical School, University of Navarra, Pamplona 31008, Spain.

Magazine: News in Physiological Sciences

Date: Apr 1, 2002

Nuclear Medicine [SP] Neurology [SP]

The basal ganglia are part of a neuronal network organized in parallel circuits.

The motor circuit is most relevant to the pathophysiology of movement. Abnormal increment or reduction in the inhibitory output activity of basal ganglia give rise, respectively, to poverty and slowness of movement (i.e., Parkinson's disease) or dyskinesias.

CITATION  News Physiol Sci. 2002 Apr;17:51-5

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