Sneddon's syndrome vasculopathy with antiphospholipid antibodies in a child

Abstract

We studied a ten-year old girl with livedo reticularis and multiple central nervous system ischemic attacks beginning when she was five. Blood tests were positive for cryoglobulins and antiphospholipid antibodies; superior limb angiography showed occlusion and irregularities of the vessel walls and temporal artery biopsy revealed concentric thickening of the vessel wall due to fibrotic subendothelial proliferation. Sneddon's syndrome was diagnosed.

Onset of this syndrome during early childhood has not been previously reported.

CITATION  Neurologia. 1995 Jan;10(1):41-5