Scientific publications

Seasons and other factors affecting the quality of life of asthmatic children

L García-Marcos (1), I Carvajal Urueña (2), A Escribano Montaner (3), M Fernández Benítez (4), S García de la Rubia (5), E Tauler Toro (6), V Pérez Fernández (1), C Barcina Sánchez (7)
(1) Institute of Respiratory Health, University of Murcia, Murcia, Spain
(2) Las Vegas Health Centre, Corvera, Asturias, Spain
(3) Pediatric Pulmonology Unit, Clinic Hospital, University of Valencia, Spain
(4) Allergy Section, University Clinic of Navarra, Pamplona, Spain
(5) Murcia Health Center, Murcia, Spain
(6) Pediatric Allergy Unit, Sant Joan de Deu Hospital, Martorell, Spain
(7) Medical Department, Astrazeneca, Spain

Magazine: Journal Investigational Allergology and Clinical Immunology

Date: Jun 1, 2007

Allergology and Immunology Department

OBJECTIVE
To study the effect of seasons on the health-related quality of life (HRQL) of asthmatic children.

METHODS
Four groups of asthmatic children 7 to 14 years old were recruited by pediatricians during each season of the year. Their HRQL was assessed by means of the Paediatric Asthma Quality of Life Questionnaire (PAQLQ). Other factors surveyed were asthma severity, atopy, medical treatment, immunotherapy, obesity, parental smoking, and anti-allergic measures.

RESULTS
The mean (SD) overall PAQLQ score was highest in summer at 6.2 (1.0) and lowest in autumn at 5.5 (1.2). The same trend was found for domains in summer and autumn, respectively: symptoms, 6.2 (1.0) vs 5.4 (1.4); emotions, 6.5 (0.8) vs 6.0 (1.0); and activities, 5.9 (1.4) vs. 5.0 (1.5). Factors such as male gender (odds ratio [OR], 0.60; 95% confidence interval [CI], 0.41-0.87), being on immunotherapy (OR, 0.59; 95% CI, 0.38-0.92), living in an urban environment (OR, 0.56; 0.33-0.93), and residing on the northern coast of Spain along the Bay of Biscay (OR, 0.56; 0.36-0.89) were independent protective factors against having a total PAQLQ score in the lower tertile. Conversely, being recruited in a primary care setting (OR, 1.55; 1.01-2.38) and having more severe asthma were risks for being in the lower tertile.

CONCLUSIONS
Irrespective of the severity of the disease, season has a significant influence on the HRQL of asthmatic children

CITATION  J Investig Allergol Clin Immunol. 2007;17(4):249-56.

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