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Phase I/II clinical trial of JK08, an IL-15 antibody fusion protein targeting CTLA-4, in patients with unresectable or metastatic advanced cancer.
THE OBJECTIVE OF THIS STUDY IS TO FIND A SAFE DOSE OF A NEW DRUG, CALLED JK08 (IMMUNOTHERAPY ANTIBODY FUSION PROTEIN THAT ACTS ON IMMUNE CELLS AND IS DESIGNED TO IMPROVE THE CAPACITY OF THE IMMUNE SYSTEM (IN PARTICULAR, T LYMPHOCYTES AND NK LYMPHOCYTES).
Technical Summary
- PHASE I/II, MULTICENTER, OPEN-LABEL, STEPWISE DOSE ESCALATION AND DOSE EXPANSION STUDY OF JK08, AN IL-15 ANTIBODY FUSION PROTEIN TARGETING CTLA-4, IN PATIENTS WITH UNRESECTABLE OR METASTATIC LOCALLY ADVANCED CANCER .STEPWISE DOSE ESCALATION
- Code EudraCT: 2022-000339-21
- Protocol number: JK08.1.01
- Promoter: Salubris Biotherapeutics, Inc.
* The trials only admit a limited number of patients and are subject to inclusion and exclusion criteria. The specialist who assesses your case will inform you of the conditions required to participate in the clinical trial.
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