PUBLICAÇÕES científicas

Therapeutic impact of colon capsule endoscopy with PillCam™ COLON 2 after incomplete standard colonoscopy: a Spanish multicenter study

Nogales Ó (1), García-Lledó J (2), Luján M (3), Nicolás D (4), Juanmartiñena JF (5), González-Suárez B (6), Sánchez Ceballos F (7), Couto I (8), Olmedo J (9), Garfia C (10), Carretero C (11), Fernández Urién  I (12), Rodríguez S (13), Asteinza M (14), Olivencia P (15), Masedo Á (16), Muñoz-Navas M (17), Merino B (2), González Asanza C (18).

(1) Servicio Aparato Digestivo, Hospital General Universitario Gregorio Marañon, España.
(2) Digestivo, Hospital General Universitario Gregorio Marañón. Madrid, ESPAÑA.
(3) Digestivo, Hospital General Universitario de Valencia.
(4) Digestivo, Hospital Universitario de Canarias.
(5) Unidad de Endoscopia. Aparato Digestivo, Complejo Hospitalario de Navarra, españa.
(6) Endoscopy Unit. Gastroenterology Department. , Hospital Clinic, Barcelona, España.
(7) Digestivo, Hospital Clínico San Carlos, España.
(8) CHU A Coruña.
(9) Digestivo, HGUCR, ESPAÑA.
(10) Digestivo, Hospital Universitario 12 de Octubre.
(11) Digestivo, Clínica Universidad de Navarra, España.
(12) Aparato Digestivo, Complejo Hospitalario de Navarra.
(13) Aparato Digestivo, Hospital Universitario 12 de Octubre, España.
(14) Aparato Digestivo, Hospital Clínico San Carlos. Madrid, ESPAÑA.
(15) Cuidad Real, Hospital General Universitario de Ciudad Real, ESPAÑA.
(16) Hospital Universitario 12 de Octubre.
(17) Aparato Digestivo, Clínica Universidad de Navarra.
(18) Aparato Digestivo, Hospital General Universitario Gregorio Marañón. Madrid, ESPAÑA.

Revisão:Revista Española de Enfermedades Digestivas

Data: 1/Mai/2017

Digestivo [ES]

INTRODUCTION:

Colon capsule endoscopy (CCE) is an alternative approach for the examination of the colon in patients who refuse colonoscopy or after incomplete colonoscopy (IC). We conducted a study to determine the frequency of complete colonoscopy after IC, the diagnostic yield of CCE, the therapeutic impact of lesions found in CCE, the level of colon cleanliness and the safety of the procedure.

METHODS:

We performed a prospective, multicenter study involving ten Spanish hospitals. Consecutive outpatients aged ≥ 18 years with previous IC were invited to participate. The latest version of the CCE device, PillCam™ COLON 2 (CCE-2), was administered to all patients according to the protocol.

RESULTS:

The study population comprised 96 patients. The most frequent cause of IC was the inability to move past a loop using standard maneuvers (75/96 patients, 78%). Complete visualization of the colon was obtained with CCE-2 in 69 patients (71.9%). Of the 27 patients in whom the CCE-2 did not reach the hemorrhoidal plexus, it passed the colonic segment explored with the previous colonoscopy in 20 cases; therefore, it could be inferred that a combined approach (CCE-2 plus colonoscopy) enabled complete visualization of the colonic mucosa in 92.7% of patients. CCE-2 revealed new lesions in 58 patients (60.4%). Polyps were the most frequent finding (41 patients; 42.7% of the total number of patients). In 43 of the 58 patients (44.8% of the total number of patients), the new lesions observed led to modification of therapy, which included a new colonoscopy for polyp resection or surgery in patients with colonic neoplasm.

CONCLUSIONS:

CCE-2 is a suitable diagnostic procedure that can lead to more frequent diagnosis of significant colonic lesions after IC.

CITAÇÃO DO ARTIGO  Rev Esp Enferm Dig. 2017 May;109(5):322-327. doi: 10.17235/reed.2017.4369/2016

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