PUBLICAÇÕES científicas
The bone-adipose axis in obesity and weight loss
Gómez-Ambrosi J, Rodríguez A, Catalán V, Frühbeck G.
Metabolic Research Laboratory, Clínica Universitaria de Navarra, University of Navarra, Avenida Pio XII 36, Pamplona, Spain.
Revisão:Obesity Surgery
Data: 1/Set/2008
Área de Obesidade Endocrinologia e Nutrição [ES]Body fat and lean mass are correlated with bone mineral density, with obesity apparently exerting protection against osteoporosis. The pathophysiological relevance of adipose tissue in bone integrity resides in the participation of adipokines in bone remodeling through effects on deposition and resorption.
On the other hand, the skeleton has recently emerged as an endocrine organ with effects on body weight control and glucose homeostasis through the actions of bone-derived factors such as osteocalcin and osteopontin. The cross-talk between adipose tissue and the skeleton constitutes a homeostatic feedback system with adipokines and molecules secreted by osteoblasts and osteoclasts representing the links of an active bone-adipose axis.
Given the impact of bariatric surgery on absorption and the adipokine secretory pattern, to focus on the changes taking place following surgical-induced weight loss on this dynamic system merits detailed consideration.
CITAÇÃO DO ARTIGO Obes Surg. 2008 Sep;18(9):1134-43. Epub 2008 Jun 19
talvezlhe interesse
QUE TECNOLOGIA UTILIZAMOS?
A Clínica é o hospital privado com maiores recursos tecnológicos de Espanha, tudo num único centro.
OS NOSSOS
PROFISSIONAIS
Os profissionais da Clínica realizam um trabalho contínuo de investigação e formação, sempre em benefício do paciente.
RAZÕES PARA VIR
À CLÍNICA
Conheça porque é que somos diferentes em relação a outros centros sanitários. Qualidade, rapidez, comodidade e resultados.
