Publicaciones científicas
Linezolid-induced lactic acidosis in two liver transplant patients with the mitochondrial DNA A2706G polymorphism
05-may-2014
| Revista: Antimicrobial Agents and Chemotherapy
Del Pozo JL (1), Fernández-Ros N (2), Sáez E (3), Herrero JI (4), Yuste JR (2), Banales JM (5).
RESUMEN
Mitochondrial toxicity has been recently suggested to be the underlying mechanism of long-term linezolid-associated toxicity in patients with 16S rRNA genetic polymorphisms.
Here, we report for the first time two cases of lactic acidosis due to long-term linezolid exposure in liver transplant recipients who presented an A2706G mitochondrial DNA polymorphism.
CITA DEL ARTÍCULO Antimicrob Agents Chemother. 2014 Jul;58(7):4227-9. doi: 10.1128/AAC.02856-14. Epub 2014 May 5.
Nuestros autores
Director
Servicio de Enfermedades Infecciosas
Sede Pamplona
Especialista
Servicio de Enfermedades Infecciosas
Sede Pamplona