Publicaciones científicas

201Tl myocardial perfusion in the management of the transplanted heart

Richter J., Herreros J., Serena A., Domper M., Ramirez J.C., Gómez A., Arcas R.
Department of Nuclear Medicine, Clínica Universitaria de Navarra, Pamplona, Spain.

Revista: European Journal of Nuclear Medicine and Molecular Imaging

Fecha: 01/01/1990

Medicina Nuclear

A semi quantitative method with thallium has been applied in the management of cardiac transplants. In all, 142 scans were performed in 20 patients and were arranged in 3 groups that represent respectively all controls performed to the transplants (G1), and a selection of the scans obtained during the 1st rejection episode in each patient (G2) and the 2nd if present (G3).

A heart/lung index was calculated through early and late images (IA, IB), obtained 5 min and 4 h post injection of thallium. A decrease in IA was detected during acute rejection in all groups.

This fall was statistically significant from the mild to moderate rejection degree in G1 (P less than 0.01), and the mild rejection in G3 (P less than 0.001). IB was not modified with rejection.

Comparing the biopsies with and without edema, in the absence of rejection, it has been proved that the intra myocardial edema can produce a decrease in IA (P less than 0.001). We conclude that IA is a simple and sensitive index to evaluate the graft, although intra myocardial edema can reduce its specificity.

CITA DEL ARTÍCULO  Eur J Nucl Med. 1990;16(3):167-71



La Clínica es el hospital privado con mayor dotación tecnológica de España, todo en un único centro.

Imagen de un PET, tecnología de vanguardia en la Clínica Universidad de Navarra


Los profesionales de la Clínica realizan una labor continuada de investigación y formación, siempre en beneficio del paciente.

Imagen profesionales de la Clínica Universidad de Navarra


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Imagen del edificio de la Clínica Universidad de Navarra