Scientific publications

Computational Fluid Dynamics Modeling of Liver Radioembolization: A Review

Jan 1, 2022 | Magazine: Cardiovascular and Interventional Radiology

Jorge Aramburu  1 , Raúl Antón  2   3 , Macarena Rodríguez-Fraile  3   4 , Bruno Sangro  3   5 , José Ignacio Bilbao  3   6


Abstract

Yttrium-90 radioembolization (RE) is a widely used transcatheter intraarterial therapy for patients with unresectable liver cancer.

In the last decade, computer simulations of hepatic artery hemodynamics during RE have been performed with the aim of better understanding and improving the therapy. In this review, we introduce the concept of computational fluid dynamics (CFD) modeling with a clinical perspective and we review the CFD models used to study RE from the fluid mechanics point of view.

Finally, we show what CFD simulations have taught us about the hemodynamics during RE, the current capabilities of CFD simulations of RE, and we suggest some future perspectives.

CITATION  Cardiovasc Intervent Radiol. 2022 Jan;45(1):12-20. doi: 10.1007/s00270-021-02956-5. Epub 2021 Sep 13.

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