PUBLICAÇÕES científicas

Targeting the basal ganglia for deep brain stimulation in Parkinson's disease

Guridi J., Rodríguez-Oroz M.C., Lozano A.M., Moro E., Albanese A., Nuttin B., Gybels J., Ramos E., Obeso J.A.
Centro de Neurocirugía Funcional, Clínica Quirón, San Sebastián, Spain. Clínica Universidad de Navarra. Pamplona, Spain.

Revisão:Neurology

Data: 1/Dez/2000

Neurologia [ES] Neurocirurgia

The revitalization of surgery for Parkinson's disease (PD) has fueled discussion about the best methodology to define the target. Placement of electrodes for deep brain stimulation (DBS) requires the usual stereotactic technique but the argument is mainly centered on whether or not microrecording neuronal activity is necessary.

We compared the accuracy of calculating the coordinates X (medio-lateral) and Y (rostro-caudal) considered by the classic stereotactic method, i.e., definition of the AC-PC intercomissural line by MRI and a digitized version of the Schaltenbrand's atlas, with final electrode placement according with microrecording and microstimulation in 21 patients.

For both the globus pallidum internum (GPi) (n = 21) and the subthalamic nucleus (STN) (n = 36) there was, respectively, a 43% and 45% mismatching of more than 3 mm between the theoretic coordinates and the final site of electrode location. This applies to both the X and Y planes. Accuracy was not improved in patients (n = 11) in whom the bilateral procedure was undertaken in a single day.

We conclude that proper electrode positioning of the STN and GPi requires fine electrophysiologic assessment.

CITAÇÃO DO ARTIGO  Neurology. 2000;55(12 Suppl 6):S21-8

talvezlhe interesse

QUE TECNOLOGIA UTILIZAMOS? 

A Clínica é o hospital privado com maiores recursos tecnológicos de Espanha, tudo num único centro.

Imagen de un PET, tecnología de vanguardia en la Clínica Universidad de Navarra

OS NOSSOS
PROFISSIONAIS

Os profissionais da Clínica realizam um trabalho contínuo de investigação e formação, sempre em benefício do paciente.

Imagen profesionales de la Clínica Universidad de Navarra

RAZÕES PARA VIR
À CLÍNICA

Conheça porque é que somos diferentes em relação a outros centros sanitários. Qualidade, rapidez, comodidade e resultados.

Imagen del edificio de la Clínica Universidad de Navarra