Publicações científicas

Paraclinical tests in multiple sclerosis. Clinical correlation and predictive value

Iriarte J., de Castro P., Artieda J. [ES], Zubieta J.L. [ES], Martínez-Lage J.M.
Departamento de Neurología, Clínica Universitaria de Navarra, Pamplona

Revisão:Neurología

Data: 1/Fev/1993

Neurologia [ES] Radiología [ES] Neurofisiologia [ES]

The correlation between clinical signs and symptoms, Evoked Potentials (EP) and Magnetic Resonance Imaging (MRI) in Multiple Sclerosis (MS) is still uncertain. It seems necessary to perform comparative studies with homogeneous groups of patients to avoid the error provoked by the selection of patients and the use in the diagnosis of EP and MRI.

The aims of this paper were to calculate the sensitivity of EP and MRI in MS in relation to time of evolution and type of MS, to determine the correlation between clinical data and EP and MRI alterations, and to show the predictive value of the paraclinical tests. We have performed clinical examination, EP and MRI in 47 patients with clinically definite MS, Poser's category 1a, without acute attack. Our results show significant correlation between VEP and visual functional scale (FS) (r = 0.43), brainstem auditory EP (BAEP) and Expanded Disability Status Scale (EDSS) (r = 0.33), BAEP and cerebellar FS (r = 0.36), BAEP and brainstem FS (r = 0.29) and somatosensory EP (SEP) and pyramidal FS (r = 0.4). Also, we found significant correlation among clinical data and MRI abnormalities in cerebellum (p < 0.01), brainstem (p < 0.001), and spinal cord (p < 0.01). The SEP (74%), cerebellar (92%) and spinal (83%) MRI alterations provided the greatest agreement with presumed clinical abnormalities.

These data confirm the efficacy of EP and MRI to describe the status of MS and support its utility to evaluate the evolution.

CITAÇÃO DO ARTIGO  Neurologia. 1993 Feb;8(2):53-8

talvezlhe interesse

QUE TECNOLOGIA UTILIZAMOS? 

A Clínica é o hospital privado com maiores recursos tecnológicos de Espanha, tudo num único centro.

Imagen de un PET, tecnología de vanguardia en la Clínica Universidad de Navarra

OS NOSSOS
PROFISSIONAIS

Os profissionais da Clínica realizam um trabalho contínuo de investigação e formação, sempre em benefício do paciente.

Imagen profesionales de la Clínica Universidad de Navarra

RAZÕES PARA VIR
À CLÍNICA

Conheça porque é que somos diferentes em relação a outros centros sanitários. Qualidade, rapidez, comodidade e resultados.

Imagen del edificio de la Clínica Universidad de Navarra