Publicaciones científicas

Epidemiology and clinical evolutionary aspects of multiple sclerosis in Navarra

Antón Aranda E. (*), Martínez-Lage J.M., Mariví Petri E., Gállego Culleré J., de Castro P., Villanueva Eúsa J.A.
Departamento de Neurología, Facultad de Medicina, Universidad de Navarra, Pamplona
(*) Servicio de Medicina Interna, Hospital de Zumárraga, Guipúzcoa

Revista: Neurología

Fecha: 01/05/1991

Neurología

In the present study 84 patients with the diagnosis of multiple sclerosis were identified as living in Navarra on the date of prevalence (December 31, 1986). The raw yearly incidence rate was 0.49/100000, which is similar to that in Mediterranean countries.

A significant increase of this rate was found between 1951 and 1986, which was interpreted as a consequence of higher economic status and/or progressive industrialization. The raw prevalence rate was 16.4/100000 and age-specific prevalence was 26.5. Therefore, Navarra is a medium risk area for MS. Mean age at onset was 29.3 years, with a significant female predominance. In addition, MS presented earlier in females. The relationship between MS and latitude of the residence area was confirmed. The most common presenting symptoms were motor (paresia) and sensory (paresthesia). Cerebrospinal fluid was abnormal in 86.5% of patients, evoked potentials (mostly visual) in 85.9%, and magnetic resonance in 100%. Demyelinizing signs were detected with CT in 29.4% of patients. The diagnostic criteria of the Boston University Workshop were highly reliable. The most common evolutive pattern was the pure remitting one.

The mean degree of disability was 3.6 in Kurtzke's scale. The evolutive form and the duration of the disease were identified as predictive of disability. 43.5% of benign forms and 13.1% of late onset forms were identified.

CITA DEL ARTÍCULO  Neurologia. 1991 May;6(5):160-9

tal vezLE INTERESE

¿QUÉ TECNOLOGÍA UTILIZAMOS?

La Clínica es el hospital privado con mayor dotación tecnológica de España, todo en un único centro.

Imagen de un PET, tecnología de vanguardia en la Clínica Universidad de Navarra

NUESTROS
PROFESIONALES

Los profesionales de la Clínica realizan una labor continuada de investigación y formación, siempre en beneficio del paciente.

Imagen profesionales de la Clínica Universidad de Navarra

POR QUÉ VENIR
A LA CLÍNICA

Conozca por qué somos diferentes a otros centros sanitarios. Calidad, rapidez, comodidad y resultados.

Imagen del edificio de la Clínica Universidad de Navarra