Publicaciones científicas

Enduring Changes in Decision Making in Patients with Full Remission from Anorexia Nervosa

31-ago-2016 | Revista: European Eating Disorders Review

Steward T (1,2), Mestre-Bach G (1,2), Agüera Z (1,2), Granero R (2,3), Martín-Romera V (4), Sánchez I (1,2), Riesco N (1,2), Tolosa-Sola I (1), Fernández-Formoso JA (2), Fernández-García JC (2,5), Tinahones FJ (2,5), Casanueva FF (2,6), Baños RM (2,7), Botella C (2,8), Crujeiras AB (2,6), de la Torre R (2,9,10), Fernández-Real JM (2,11), Frühbeck G (2,12), Ortega FJ (2,11), Rodríguez A (2,12), Jiménez-Murcia S (1,2,13), Menchón JM (1,13,14), Fernández-Aranda F (1,2,13).


BACKGROUND:
Deficits in neuropsychological functioning have consistently been identified in patients with anorexia nervosa (AN). However, little is known on how decision making in AN patients evolves in response to treatment or whether impairments are reversible.

METHOD:
AN patients (n = 42) completed the Iowa Gambling Task (IGT) upon admission to a 3-month day-hospital treatment programme and at a 1-year follow-up. Patient IGT performance was compared to age-matched controls (n = 46).

RESULTS:
AN patients displayed poorer performance on the IGT at admission compared to controls (p < .001). Patients with full remission (n = 31; 73.9%) at the 1-year follow-up improved IGT performance (p = 0.007), and scores were similar compared to controls (p = 0.557). AN patients with partial/no remission at follow-up (n = 11; 26.1%) did not improve IGT scores (p = 0.867).

CONCLUSIONS:
These findings uphold that enduring remission from AN can reverse decision-making impairments, and they might be most likely explained by clinical state rather than a trait vulnerability.

CITA DEL ARTÍCULO  Eur Eat Disord Rev. 2016 Nov;24(6):523-527.  doi: 10.1002/erv.2472.  Epub 2016 Aug 31.