Recognition and management of hereditary colorectal cancer syndromes
Magazine: Revista Española de Enfermedades de Digestivas
Date: Aug 21, 2009Digestive Tract Tumours Area Digestive [SP]
Over 1.900 colorectal tumors will arise in association with a hereditary colorectal cancer syndrome in Spain in 2009. The genetic defects responsible for the most common syndromes have been discovered in recent years.
Genetic testing helps diagnose affected individuals and allows identification of individuals at-risk. Colonoscopy and prophylactic colectomy decrease colorectal cancer incidence and overall mortality in patients with hereditary colon cancer.
Extracolonic tumors are frequent in these syndromes, so specific surveillance strategies should be offered.
CITATION Rev Esp Enferm Dig. 2009 Feb;101(2):125-32
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