Rat atrial natriuretic peptide stimulates K+ fluxes in human erythrocytes
Esparza N., Díez J.
Servicio de Nefrología, Clínica Universitaria, Universidad de Navarra, Spain.
Magazine: The European Journal of Pharmacology
Date: Jul 1, 1989Cardiology
Ouabain- and bumetanide-resistant potassium fluxes were measured in human erythrocytes incubated in a medium containing calcium and a calcium ionophore.
Pharmacological concentrations of rat atrial natriuretic peptide stimulated these fluxes. Although human erythrocytes lack atrial natriuretic peptide receptors, our results suggest that the hormone can modify transmembrane K+ movements.
CITATION Eur J Pharmacol. 1989 Jul 18;166(2):349-52
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