Scientific publications

Prognostic value of local vascular infiltration in infiltrating transitional carcinoma of the bladder

de Castro F, Sánchez P, Robledo C, Rosell D [SP], Agüera L, Isa W, Robles JE [SP], Berián JM.
Departamento de Urología, Facultad de Medicina, Universidad de Navarra

Magazine: Actas Urológicas Españolas

Date: Apr 1, 1992

Urology [SP]

The present retrospective study analyzes the evolution and survival of 79 patients with bladder infiltrant transitional carcinoma (T2-T3), which were treated with radical cystectomy and bilateral ilio-obturating lymphadenectomy. Pre-operative radiotherapy (57/79) and neo-adjuvant chemotherapy (24/79) was used as supplementary therapy.

The univariate analysis showed the relationship between tumour vascular infiltration (TVI) and presence of nodes micrometastasis (p = 0.002). The variables with greater forecast power in the multivariate analysis for survival were a decline in the post-radio and/or neo-adjuvant chemotherapy tumoral stage (p = 0.000) and TVI (p = 0.001).

Survival decreased significantly in patients with TVI (p = 0.008), this finding denoting a worse prognosis than the presence of nodular micrometastasis (p = 0.01).

CITATION  Actas Urol Esp. 1992 Apr;16(4):321-4

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