Scientific publications

Multidrug-resistant tuberculosis presenting as a solitary splenic mass in an immunocompetent patient

Rojo A, Ibáñez MA, Alonso CA, Portillo ME, Quintana J, Yuste JR [SP], Del Pozo JL [SP].
Department of Clinical Microbiology, Clinica Universidad de Navarra, Avenida Pio XII no. 36 (31008), Pamplona, Spain

Magazine: Diagnostic Microbiology and Infectious Disease

Date: Aug 1, 2011

Infectious Diseases [SP] Clinical Microbiology [SP]

Here, we report a case of multidrug-resistant tuberculosis (TB) presenting as a solitary splenic mass in a 60-year-old immunocompetent patient. Splenic TB is unusual and, when present, is usually associated with disseminated disease in immunocompromised patients.

A high level of suspicion is required for diagnosis, and, as occurred in our case, it may be an unexpected finding following surgery. Diagnosis was made by polymerase chain reaction, which showed the presence of Mycobacterium tuberculosis DNA. Interestingly, rifampicin- and isoniazid-resistant genes were detected in our analysis. Splenic TB diagnosis and treatment are reviewed.

CITATION  Diagn Microbiol Infect Dis. 2011 Aug;70(4):522-4

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