Scientific publications

Motor complications in patients with Parkinson disease treated with levodopa

Luquin MR, Obeso JA, Martínez-Lage JM.
Department of Neurology. Clínica Universitaria de Navarra.

Magazine: Neurología

Date: Feb 1, 1989

Neurology [SP]

Motor complications appearing in 180 patients with Parkinson's disease who received levodopa for a long period are reviewed. The most frequently observed motor disorders were wearing off fluctuations and dyskinesias of dose benefit.

Most patients who presented a decrease in the response to levodopa developed signs during the course or findings in complementary tests which were incompatible with the diagnosis of Parkinson's disease. In the present study, the duration of the treatment with levodopa and the duration of the disease varied in parallel in such a way that it was not possible to individualize the relative importance of both factors in the development of the observed motor complications.

CITATION  Neurologia. 1989 Jan-Feb;4(1):4-11

you maybe interested


The Clínica is the greater private hospital with technological equipment of Spain, all in a single center.

Imagen de un PET, tecnología de vanguardia en la Clínica Universidad de Navarra


The professionals of the Clínica perform continuous research and training, always to the benefit of the patient.

Imagen profesionales de la Clínica Universidad de Navarra


Learn why we are different from other healthcare centers. Quality, speed, comfort and results.

Imagen del edificio de la Clínica Universidad de Navarra