Scientific publications

Monitoring of everolimus trough concentrations for achieving optimal tolerance in the management of tuberous sclerosis complex

Landecho MF [SP] (1), Alegre F [SP] (2), Lucena JF [SP] (2), Huerta A [SP] (2), Fernández-Ros N (2), Aldaz A [SP] (3).
(1) Unidad de Médicos Hospitalistas-Área de Hospitalización Especial, Departamento de Medicina Interna, Clínica Universidad de Navarra, Pamplona, Navarra, España.
(2) Unidad de Médicos Hospitalistas-Área de Hospitalización Especial, Departamento de Medicina Interna, Clínica Universidad de Navarra, Pamplona, Navarra, España.
(3) Servicio de Farmacia, Clínica Universidad de Navarra, Pamplona, Navarra, España. 

Magazine: Pediatric Neurology

Date: Sep 1, 2014

Pharmacy [SP] Internal Medicine [SP]

ABSTRACT

Tuberous sclerosis complex (TSC) is a genetic disorder characterized by the development of a variety of benign tumors along with an increased risk of malignancy. Mechanism of disease is related to the mTOR pathway.1 In spite of this, individual features have different natural histories, and it is difficult to predict the extent to which a child with newly diagnosed disease is affected.

CITATION  Pediatr Neurol. 2014 Sep;51(3):e9-10. doi: 10.1016/j.pediatrneurol.2014.05.019. Epub 2014 May 29.

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