Scientific publications

Mitochondrial diseases and stroke

Irimia P. [SP], Oliveros-Cid A., Martínez-Vila E.
Departamento de Neurología y Neurocirugía, Clínica Universitaria de Navarra, Facultad de Medicina, Universidad de Navarra, Pamplona, España

Magazine: Revsita de Neurología

Date: Apr 1, 1998

Neurology [SP]

We review the mitochondrial diseases in which cerebrovascular changes are seen, such as the MERRF syndrome (myoclonic epilepsy and ragged red fibers) or the Kearns-Sayre syndrome (progressive external ophthalmoplegia, retinitis pigmentaria, cerebellar disorders and disorders of cardiac conduction), focusing on the syndrome involving mitochondrial encephalomyopathy, lactic acidosis and stroke-like episodes (MELAS).

We consider the different clinical aspects, diagnostic methods, pathophysiological mechanisms of the cerebrovascular involvement as well as therapeutic approaches.

CITATION  Rev Neurol. 1998 Apr;26 Suppl 1:S99-106

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