Scientific publications

Incidental findings in negative sentinel lymph nodes of patients with malignant melanoma: report of three cases

Martinez-Peñuela, Ana MD (1); Olmo, Julio Del MD (2); Boán, José Francisco MD (3); Idoate, Miguel Angel [SP] MD (1)
(1) Department of Pathology; (2) Department of Dermatology; and (3) Nuclear Medicine Department; Clínica Universitaria de Navarra, Pamplona, Spain.

Magazine: The American Journal of Dermatopathology

Date: Feb 1, 2007

Breast Cancer Area Pathological Anatomy [SP]

We present three cases of benign SLN that were clinically suspicious for involvement by metastatic melanoma and where found to be involved with other diseases or deposits previously unknown, A 44-year-old woman presented with a 1.6 cm pigmented lesion on her back.

An excisional skin biopsy revealed a 1.7-mm-thick superficial spreading melanoma. The patient had bilateral silicone breast prostheses. An axillary sentinel lymph node (SLN) excision was performed. The lymph node examination showed a granulomatous reaction, with numerous macrophages.

There was no evidence of metastatic melanoma by immunohistochemical studies with S-100, Melan-A, and HMB-45.

CITATION Am J Dermatopathol. 2007 Feb;29(1):104-5

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