Scientific publications

High frequency oscillations in the somatosensory evoked potentials (SSEP's) are mainly due to phase-resetting phenomena

Valencia M, Alegre M [SP], Iriarte J, Artieda J. [SP]
Neurophysiology Laboratory, Centre for Applied Medical Research, Universidad de Navarra, Pamplona, Spain.

Magazine: Journal of Neuroscience Methods

Date: Jun 30, 2006

Neurophysiology [SP]


A small series of high frequency oscillations (HFOs) overlapping the earliest part of the N20 wave can be observed in the somatosensory evoked potentials (SSEPs) of normal subjects. We tried to elucidate whether these high frequency components are mainly due to phase-resetting phenomena, to the emergence of new oscillations related to the stimuli, or to a combination of both. Averaged median-nerve SSEPs from seven healthy subjects were studied by means of time-frequency analysis.

The presence of new oscillatory activities was evaluated by averaging the energy of the single-trial time-frequency transforms in the HFOs range (400-1000 Hz). To study phase-resetting phenomena, we measured inter-trial coherence (ITC) in the same frequency range. A marked inter-trial coherence related to the HFOs was found, whereas energy changes (related to the emergence of new oscillations) were minimal.

The combination of these three different approaches suggests that the HFOs are mainly due to resettings of the ongoing EEG activity originated in response to the stimuli. The emergence of new activities does not seem to be a relevant mechanism in the formation of these components.

CITATION  J Neurosci Methods. 2006 Jun 30;154(1-2):142-8

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