Efficacy of transjugular intrahepatic portosystemic shunt to prevent total portal vein thrombosis in cirrhotic patients awaiting for liver transplantation
D'Avola D [SP], Bilbao JI, Zozaya G, Pardo F, Rotellar F, Iñarrairaegui M [SP], Quiroga J [SP], Sangro B, Herrero JI.
Liver Unit and CIBERehd (Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas), Clinica Universidad de Navarra, Pamplona, Spain
Magazine: Transplantation Proceedings
Date: Nov 1, 2012Radiology [SP] General and Digestive Surgery Hepatology
Complete portal vein thrombosis (PVT) may complicate orthotopic liver transplantation (OLT), increasing its technical difficulty and the transfusion requirements and as well as affecting survival in some cases. Transjugular intrahepatic portosystemic shunt (TIPS) prevents total portal vein occlusion in patients with partial PVT.
We aimed to assess the efficacy and safety of TIPS to prevent total portal vein occlusion among patients listed for OLT.
PATIENTS AND METHODS
We analyzed the clinical records of 15 consecutive patients with partial PVT who underwent TIPS before OLT. The control group consisted of 8 transplanted patients without TIPS but partial PVT diagnosed before OLT. Portal vein patency at surgery, ischemia time, and transfusion requirements during OLT, and survival thereafter were compared between both groups. The main complications were also compared: mortality after TIPS (from TIPS placement to OLT), intraoperative technical complications, and technical complications during the 6 months after OLT.
Clinical characteristics at the time of OLT were similar between the groups. No relevant complications were observed after TIPS; all patients underwent transplantation. One- and 5-year actuarial survival rates were similar in both groups (92% and 85% in TIPS-group versus 100 and 75% in the control group, respectively). No differences in transfusion requirement, duration of ischemia, and frequency of technical complications during and after OLT were observed between the groups. The portal vein was patent at surgery in all TIPS patients and 4 of 8 (50%) in the control group (P = .008).
TIPS may prevent PVT in liver transplantation candidates with partial PVT.
CITATION Transplant Proc. 2012 Nov;44(9):2603-5. doi: 10.1016/j.transproceed.2012.09.050
you mayBE INTERESTED
The Clínica is the greater private hospital with technological equipment of Spain, all in a single center.
The professionals of the Clínica perform continuous research and training, always to the benefit of the patient.
Learn why we are different from other healthcare centers. Quality, speed, comfort and results.